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The company said that Microsoft's technology, which is used to create add-ins for Internet Explorer, accounted for some 79 per cent of the 239 plug-in bugs discovered between July and December last year.
In comparison, the next-highest number of flaws was from Apple's QuickTime, which scored just 8 per cent of the total.
And only one vulnerability was found in a plug-in for Mozilla's Firefox browser - or about 0.4 percent of all detected flaws.
Symantec said that this result was due to several factors, including the availability of tools that hackers use to exploit input vulnerabilities in the controls.